Combined-Modality Therapy for Head and Neck Cancer
نویسنده
چکیده
Chemotherapy has often been combined with radiotherapy and/or surgery in the treatment of patients with advanced head and neck cancer in an attempt to improve locoregional control, decrease distant metastasis, and increase survival. Recently, induction chemotherapy has been used in the selection of patients with advanced resectable carcinoma of the larynx and hypopharynx for organ preservation.[1,2] Patients who achieve complete or partial responses to chemotherapy are candidates for organ preservation with subsequent radiotherapy.
منابع مشابه
A Review on the Efficacy of Chemotherapy in Locally Advanced Head and Neck Cancers
Background and Aims: Chemotherapy is utilized as a part of combined-modality programs to achieve organ preservation and improve survival in patients with locally advanced head and neck cancer. Combinedmodality protocols can be used in three forms: a) neoadjuvant induction chemotherapy before definitive surgery or radiotherapy; b) concomitant chemoradiotherapy; and c) sequential therapy consisti...
متن کاملRecent new approaches to the treatment of head and neck cancer.
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer in the world and affects 50,000 Americans annually. During the past 20 years, treatments for HNSCC have changed dramatically due largely to the advent of novel approaches such as combined modality therapy, as well as improvements in surgical and radiotherapeutic techniques. Ongoing advances in the multidisciplinary ma...
متن کاملDecreased hearing after combined modality therapy for head and neck cancer.
PURPOSE Combined platinum-based chemoradiation therapy is frequently being used as therapy for head and neck cancer at multiple sites. These therapies are individually ototoxic, but little has been reported on their combined toxicity. MATERIALS AND METHODS A retrospective investigation of 37 patients known to have undergone therapy with both agents, in combination, for head and neck malignanc...
متن کاملEvolving strategies for combined-modality therapy for locally advanced head and neck cancer.
Despite continual advances in the treatment of head and neck cancer, disease-free survival, functional outcome, toxicity of therapy, and overall survival remain less than optimal. While traditional treatment has focused on surgical resection with or without radiation and chemoradiotherapy, newer combined-modality regimens may offer patients a better prognosis, organ preservation, and less morbi...
متن کاملCombined-Modality Therapy of Head and Neck Cancer
Head and neck cancer occurs at an incidence of approximately 40,000 cases annually in the United States.[1] Approximately one-third of patients present with early-stage disease, which is usually cured with single-modality surgery or radiation therapy.[2] The great majority of the remaining patients present with locoregionally advanced disease, ie, large primaries (T3, T4) and/or involvement of ...
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تاریخ انتشار 2017